FCGR2A Promoter Methylation and Risks for Intravenous Immunoglobulin Treatment Responses in Kawasaki Disease

Kawasaki disease (KD) is characterized by pediatric systemic vasculitis of an unknown cause. The low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) gene was reported to be involved in the susceptibility of KD. DNA methylation is one of the epigenetic mechanisms that control gene expr...

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Bibliographic Details
Main Authors: Ho-Chang Kuo, Yu-Wen Hsu, Mei-Shin Wu, Peng Yeong Woon, Henry Sung-Ching Wong, Li-Jen Tsai, Ruo-Kai Lin, Sukhontip Klahan, Kai-Sheng Hsieh, Wei-Chiao Chang
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/564625