Fibronectin and laminin promote differentiation of human mesenchymal stem cells into insulin producing cells through activating Akt and ERK

<p>Abstract</p> <p>Background</p> <p>Islet transplantation provides a promising cure for Type 1 diabetes; however it is limited by a shortage of pancreas donors. Bone marrow-derived multipotent mesenchymal stem cells (MSCs) offer renewable cells for generating insulin-p...

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Bibliographic Details
Main Authors: Chiou Shih-Hwa, Chen Ling-Lan, Tsai Chih-Chien, Lin Hsiao-Yun, Wang Yng-Jiin, Hung Shih-Chieh
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/17/1/56