Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis

Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis

Abstract The choroid plexus (CP) is a highly vascularized structure located in the ventricles that forms the blood-CSF barrier (BCSFB) and separates the blood from the cerebrospinal fluid (CSF). In addition to its role as a physical barrier, the CP functions in CSF secretion, transport of nutrients...

Full description

Bibliographic Details
Main Authors: J. Saul, E. Hutchins, R. Reiman, M. Saul, L. W. Ostrow, B. T. Harris, K. Van Keuren-Jensen, R. Bowser, N. Bakkar
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Acta Neuropathologica Communications
Subjects:
Choroid plexus
ALS
Blood-CSF barrier
RNA sequencing
Tight junctions
Online Access:http://link.springer.com/article/10.1186/s40478-020-00968-9

Internet

http://link.springer.com/article/10.1186/s40478-020-00968-9

Similar Items