Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis
Abstract The choroid plexus (CP) is a highly vascularized structure located in the ventricles that forms the blood-CSF barrier (BCSFB) and separates the blood from the cerebrospinal fluid (CSF). In addition to its role as a physical barrier, the CP functions in CSF secretion, transport of nutrients...
Main Authors: | J. Saul, E. Hutchins, R. Reiman, M. Saul, L. W. Ostrow, B. T. Harris, K. Van Keuren-Jensen, R. Bowser, N. Bakkar |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-06-01
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Series: | Acta Neuropathologica Communications |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40478-020-00968-9 |
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