SMAD3 rs17228212 gene polymorphism is associated with reduced risk to cerebrovascular accidents and subclinical atherosclerosis in anti-CCP negative Spanish rheumatoid arthritis patients.

SMAD3 rs17228212 gene polymorphism is associated with reduced risk to cerebrovascular accidents and subclinical atherosclerosis in anti-CCP negative Spanish rheumatoid arthritis patients.

UNLABELLED:Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated atherosclerosis and increased risk of cardiovascular (CV) disease. Previous genome-wide association studies have described SMAD3 rs17228212 polymorphism as an important signal associated with...

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Bibliographic Details
Main Authors: Mercedes García-Bermúdez, Raquel López-Mejías, Fernanda Genre, Santos Castañeda, Carlos González-Juanatey, Javier Llorca, Alfonso Corrales, José A Miranda-Filloy, Javier Rueda-Gotor, Carmen Gómez-Vaquero, Luis Rodríguez-Rodríguez, Benjamín Fernández-Gutiérrez, Dora Pascual-Salcedo, Alejandro Balsa, Francisco J López-Longo, Patricia Carreira, Ricardo Blanco, Isidoro González-Álvaro, Javier Martín, Miguel A González-Gay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3804609?pdf=render

Internet

http://europepmc.org/articles/PMC3804609?pdf=render

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