Mitochondrial dysfunctions in leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).

Mitochondrial dysfunctions in leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).

Several inherited human diseases have been linked to mitochondrial aminoacyl-tRNA synthetases (mtARSs). Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) is a leukodystrophy caused by mutations in the DARS2 gene which encodes mitochondrial aspartyl-tRNA synt...

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Bibliographic Details
Main Authors: Tsu-Kung Lin, Yung-Yee Chang, Hung-Yu Lin, Chia-Wei Liou, Pei-Wen Wang, Jiin-Haur Chuang, Shang-Der Chen, Yao-Chung Chuang, Sheng-Teng Huang, Te-Yao Hsu, Cheng-Huei Peng, Min-Yu Lan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224173

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https://doi.org/10.1371/journal.pone.0224173

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