Elucidating Duramycin’s Bacterial Selectivity and Mode of Action on the Bacterial Cell Envelope

The use of naturally occurring antimicrobial peptides provides a promising route to selectively target pathogenic agents and to shape microbiome structure. Lantibiotics, such as duramycin, are one class of bacterially produced peptidic natural products that can selectively inhibit the growth of othe...

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Bibliographic Details
Main Authors: Sahar Hasim, David P. Allison, Berlin Mendez, Abigail T. Farmer, Dale A. Pelletier, Scott T. Retterer, Shawn R. Campagna, Todd B. Reynolds, Mitchel J. Doktycz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00219/full