Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model

Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model

Abstract Background Duchenne muscular dystrophy (DMD) associated cardiomyopathy is a major cause of morbidity and mortality. In an in vitro DMD cardiomyocyte model, nicorandil reversed stress-induced cell injury through multiple pathways implicated in DMD. We aimed to test the efficacy of nicorandil...

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Bibliographic Details
Main Authors: Rachel T. Sullivan, Ngoc T. Lam, Margaret Haberman, Margaret J. Beatka, Muhammad Z. Afzal, Michael W. Lawlor, Jennifer L. Strande
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Cardiovascular Disorders
Subjects:
Duchenne muscular dystrophy
DMD
Cardiomyopathy
Nicorandil
Online Access:https://doi.org/10.1186/s12872-021-02112-4

Internet

https://doi.org/10.1186/s12872-021-02112-4

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