Type I Interferons and Malaria: A Double-Edge Sword Against a Complex Parasitic Disease

Type I Interferons and Malaria: A Double-Edge Sword Against a Complex Parasitic Disease

Type I interferons (IFN-Is) are important cytokines playing critical roles in various infections, autoimmune diseases, and cancer. Studies have also shown that IFN-Is exhibit ‘conflicting’ roles in malaria parasite infections. Malaria parasites have a complex life cycle with multiple developing stag...

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Bibliographic Details
Main Authors: Xiao He, Lu Xia, Keyla C. Tumas, Jian Wu, Xin-Zhuan Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
IFN-Is
Plasmodium
immune response
signaling pathways
virulence
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.594621/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2020.594621/full

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