In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells.

In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells.

Dapsone (DDS) hydroxylamine metabolites cause oxidative stress- linked adverse effects in patients, such as methemoglobin formation and DNA damage. This study evaluated the ameliorating effect of the antioxidant resveratrol (RSV) on DDS hydroxylamine (DDS-NHOH) mediated toxicity in vitro using human...

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Bibliographic Details
Main Authors: Rosyana V Albuquerque, Nívea S Malcher, Lílian L Amado, Michael D Coleman, Danielle C Dos Santos, Rosivaldo Sa Borges, Sebastião Aldo S Valente, Vera C Valente, Marta Chagas Monteiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4540410?pdf=render

Internet

http://europepmc.org/articles/PMC4540410?pdf=render

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