First-Trimester Maternal Folic Acid Supplementation Modifies the Effects of Risk Factors Exposures on Congenital Heart Disease in Offspring

First-Trimester Maternal Folic Acid Supplementation Modifies the Effects of Risk Factors Exposures on Congenital Heart Disease in Offspring

This study aimed to examine effect modification of maternal risk factor exposures and congenital heart disease (CHD) by maternal folic acid supplementation (FAS)/non-FAS. We included 8379 CHD cases and 6918 CHD-free controls from 40 clinical centers in Guangdong Province, Southern China, 2004–2016....

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Bibliographic Details
Main Authors: Yanji Qu, Shao Lin, Michael S. Bloom, Ximeng Wang, Zhiqiang Nie, Yanqiu Ou, Jinzhuang Mai, Xiangmin Gao, Yong Wu, Jimei Chen, John Justino, Hongzhuan Tan, Jian Zhuang, Xiaoqing Liu
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Life
Subjects:
congenital heart diseases
folic acid
risk factors
interaction
Online Access:https://www.mdpi.com/2075-1729/11/8/724

Internet

https://www.mdpi.com/2075-1729/11/8/724

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