Autophagic and Apoptotic Pathways as Targets for Chemotherapy in Glioblastoma

Autophagic and Apoptotic Pathways as Targets for Chemotherapy in Glioblastoma

Glioblastoma multiforme is the most malignant and aggressive type of brain tumor, with a mean life expectancy of less than 15 months. This is due in part to the high resistance to apoptosis and moderate resistant to autophagic cell death in glioblastoma cells, and to the poor therapeutic response to...

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Bibliographic Details
Main Authors: Cristina Trejo-Solís, Norma Serrano-Garcia, Ángel Escamilla-Ramírez, Rosa A. Castillo-Rodríguez, Dolores Jimenez-Farfan, Guadalupe Palencia, Minerva Calvillo, Mayra A. Alvarez-Lemus, Athenea Flores-Nájera, Arturo Cruz-Salgado, Julio Sotelo
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma
apoptosis
autophagia
signaling pathways
therapeutic targets
chemotherapy
Online Access:https://www.mdpi.com/1422-0067/19/12/3773

Internet

https://www.mdpi.com/1422-0067/19/12/3773

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