Deletion of arginase 2 attenuates neuroinflammation in an experimental model of optic neuritis.

Vision impairment due to optic neuritis (ON) is one of the major clinical presentations in Multiple Sclerosis (MS) and is characterized by inflammation and degeneration of the optic nerve and retina. Currently available treatments are only partially effective and have a limited impact on the neuroin...

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Bibliographic Details
Main Authors: Amritha A Candadai, Fang Liu, Abdelrahman Y Fouda, Moaddey Alfarhan, Chithra D Palani, Zhimin Xu, Ruth B Caldwell, S Priya Narayanan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0247901