RNAseq and quantitative proteomic analysis of Dictyostelium knock-out cells lacking the core autophagy proteins ATG9 and/or ATG16

RNAseq and quantitative proteomic analysis of Dictyostelium knock-out cells lacking the core autophagy proteins ATG9 and/or ATG16

Abstract Background Autophagy is an evolutionary ancient mechanism that sequesters substrates for degradation within autolysosomes. The process is driven by many autophagy-related (ATG) proteins, including the core members ATG9 and ATG16. However, the functions of these two core ATG proteins still n...

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Bibliographic Details
Main Authors: Qiuhong Xiong, Ning Song, Ping Li, Sarah Fischer, Roman Konertz, Prerana Wagle, Gernot Glöckner, Changxin Wu, Ludwig Eichinger
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Genomics
Subjects:
Autophagy
ATG9
ATG16
RNAseq
proteome
tandem mass tag (TMT)
Online Access:https://doi.org/10.1186/s12864-021-07756-2

Internet

https://doi.org/10.1186/s12864-021-07756-2

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