Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta

Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta

Cryo-EM has revealed the structures of many challenging yet exciting macromolecular assemblies at near-atomic resolution (3–4.5Å), providing biological phenomena with molecular descriptions. However, at these resolutions, accurately positioning individual atoms remains challenging and error-prone. M...

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Bibliographic Details
Main Authors: Ray Yu-Ruei Wang, Yifan Song, Benjamin A Barad, Yifan Cheng, James S Fraser, Frank DiMaio
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
cryo-EM
structure refinement
atomic models
Rosetta
macromolecular assemblies
membrane proteins
Online Access:https://elifesciences.org/articles/17219

Internet

https://elifesciences.org/articles/17219

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