Multi-Omics Profiling of the Tumor Microenvironment: Paving the Way to Precision Immuno-Oncology

Multi-Omics Profiling of the Tumor Microenvironment: Paving the Way to Precision Immuno-Oncology

The tumor microenvironment (TME) is a multifaceted ecosystem characterized by profound cellular heterogeneity, dynamicity, and complex intercellular cross-talk. The striking responses obtained with immune checkpoint blockers, i.e., antibodies targeting immune-cell regulators to boost antitumor immun...

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Bibliographic Details
Main Authors: Francesca Finotello, Federica Eduati
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Oncology
Subjects:
tumor-infiltrating immune cells
bioinformatics
tumor microenvironment
multi-omics profiling
next-generation sequencing
systems biology
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00430/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00430/full

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