The Host Protein Aquaporin-9 is Required for Efficient Plasmodium falciparum Sporozoite Entry into Human Hepatocytes

The Host Protein Aquaporin-9 is Required for Efficient Plasmodium falciparum Sporozoite Entry into Human Hepatocytes

Hepatocyte invasion by Plasmodium sporozoites represents a promising target for innovative antimalarial therapy, but the molecular events mediating this process are still largely uncharacterized. We previously showed that Plasmodium falciparum sporozoite entry into hepatocytes strictly requires CD81...

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Bibliographic Details
Main Authors: Nadia Amanzougaghene, Shahin Tajeri, Samir Yalaoui, Audrey Lorthiois, Valérie Soulard, Audrey Gego, Armelle Rametti, Véronica Risco-Castillo, Alicia Moreno, Maurel Tefit, Geert-Jan van Gemert, Robert W. Sauerwein, Jean-Christophe Vaillant, Philippe Ravassard, Jean-Louis Pérignon, Patrick Froissard, Dominique Mazier, Jean-François Franetich
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Plasmodium falciparum
sporozoites
liver stage
hepatocytes
Aquaporin-9
CD81
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.704662/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.704662/full

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