The Multifaceted Role of Plasminogen in Cancer

The Multifaceted Role of Plasminogen in Cancer

Fibrinolytic factors like plasminogen, tissue-type plasminogen activator (tPA), and urokinase plasminogen activator (uPA) dissolve clots. Though mere extracellular-matrix-degrading enzymes, fibrinolytic factors interfere with many processes during primary cancer growth and metastasis. Their many rec...

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Bibliographic Details
Main Authors: Beate Heissig, Yousef Salama, Taro Osada, Ko Okumura, Koichi Hattori
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
cancer
plasminogen
metastasis
drug resistance
exosomes
uPAR
Online Access:https://www.mdpi.com/1422-0067/22/5/2304

Internet

https://www.mdpi.com/1422-0067/22/5/2304

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