Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate IL-6-induced acute liver injury through miR-455-3p

Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate IL-6-induced acute liver injury through miR-455-3p

Abstract Background Using a toxin-induced nonhuman primate model of acute liver failure (ALF), we previously reported that peripheral infusion of human umbilical cord mesenchymal stem cells (hUC-MSCs) strongly suppresses the activation of circulating monocytes and interleukin-6 (IL-6) production, th...

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Bibliographic Details
Main Authors: Mingyang Shao, Qing Xu, Zhenru Wu, Yuwei Chen, Yuke Shu, Xiaoyue Cao, Menglin Chen, Bo Zhang, Yongjie Zhou, Rong Yao, Yujun Shi, Hong Bu
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Subjects:
Exosome
microRNA-455-3p
hUC-MSCs
Inflammation
Acute liver injury
Online Access:https://doi.org/10.1186/s13287-020-1550-0

Internet

https://doi.org/10.1186/s13287-020-1550-0

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