Expression of Genes for Drug Transporters in the Human Female Genital Tract and Modulatory Effect of Antiretroviral Drugs.

Expression of Genes for Drug Transporters in the Human Female Genital Tract and Modulatory Effect of Antiretroviral Drugs.

Anti-retroviral (ARV) -based microbicides are one of the strategies pursued to prevent HIV-1 transmission. Delivery of ARV drugs to subepithelial CD4+ T cells at concentrations for protection is likely determined by drug transporters expressed in the cervicovaginal epithelium. To define the role of...

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Main Authors: Karolin Hijazi, Anna M Cuppone, Kieron Smith, Maria A Stincarelli, Julia Ekeruche-Makinde, Giulia De Falco, Georgina L Hold, Robin Shattock, Charles G Kelly, Gianni Pozzi, Francesco Iannelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4477895?pdf=render

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http://europepmc.org/articles/PMC4477895?pdf=render

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