Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome[S]

Lipid modifications aid in regulating (and misregulating) protein function and localization. However, efficient methods to screen for a lipid's ability to modify proteins are not readily available. We present a strategy to identify protein-reactive lipids and apply it to a neurodevelopmental di...

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Bibliographic Details
Main Authors: Katherine Windsor, Thiago C. Genaro-Mattos, Hye-Young H. Kim, Wei Liu, Keri A. Tallman, Sayuri Miyamoto, Zeljka Korade, Ned A. Porter
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520353098