NRAS and BRAF mutations in melanoma-associated nevi and uninvolved nevi.

NRAS and BRAF mutations in melanoma-associated nevi and uninvolved nevi.

According to the prevailing multistep model of melanoma development, oncogenic BRAF or NRAS mutations are crucial initial events in melanoma development. It is not known whether melanocytic nevi that are found in association with a melanoma are more likely to carry BRAF or NRAS mutations than uninvo...

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Bibliographic Details
Main Authors: Philipp Tschandl, Anna Sophie Berghoff, Matthias Preusser, Sebastian Burgstaller-Muehlbacher, Hubert Pehamberger, Ichiro Okamoto, Harald Kittler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3704624?pdf=render

Internet

http://europepmc.org/articles/PMC3704624?pdf=render

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