Avidity of anti-circumsporozoite antibodies following vaccination with RTS,S/AS01E in young children.

The nature of protective immune responses elicited by immunization with the candidate malaria vaccine RTS,S is still incompletely understood. Antibody levels correlate with protection against malaria infection, but considerable variation in outcome is unexplained (e.g., children may experience malar...

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Bibliographic Details
Main Authors: Ally Olotu, Frederic Clement, Erik Jongert, Johan Vekemans, Patricia Njuguna, Francis M Ndungu, Kevin Marsh, Geert Leroux-Roels, Philip Bejon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4266636?pdf=render