Delivery of Alpha-Mangostin Using Cyclodextrins through a Biological Membrane: Molecular Dynamics Simulation

Delivery of Alpha-Mangostin Using Cyclodextrins through a Biological Membrane: Molecular Dynamics Simulation

α-Mangostin (MGS) exhibits various pharmacological activities, including antioxidant, anticancer, antibacterial, and anti-inflammatory properties. However, its low water solubility is the major obstacle for its use in pharmaceutical applications. To increase the water solubility of MGS, complex form...

Full description

Bibliographic Details
Main Authors: Wiparat Hotarat, Bodee Nutho, Peter Wolschann, Thanyada Rungrotmongkol, Supot Hannongbua
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
alpha-mangostin
cellular membrane
POPC
cyclodextrins
drug penetration
molecular dynamics
Online Access:https://www.mdpi.com/1420-3049/25/11/2532

Internet

https://www.mdpi.com/1420-3049/25/11/2532

Similar Items