Transcriptional activation of prostate specific homeobox gene NKX3-1 in subsets of T-cell lymphoblastic leukemia (T-ALL).

Homeobox genes encode transcription factors impacting key developmental processes including embryogenesis, organogenesis, and cell differentiation. Reflecting their tight transcriptional control, homeobox genes are often embedded in large non-coding, cis-regulatory regions, containing tissue specifi...

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Bibliographic Details
Main Authors: Stefan Nagel, Stefan Ehrentraut, Jürgen Tomasch, Stefan Lienenklaus, Björn Schneider, Robert Geffers, Corinna Meyer, Maren Kaufmann, Hans G Drexler, Roderick A F MacLeod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3407137?pdf=render