Nanodroplet processing platform for deep and quantitative proteome profiling of 10–100 mammalian cells

Nanodroplet processing platform for deep and quantitative proteome profiling of 10–100 mammalian cells

There is a great need of developing highly sensitive mass spectrometry-based proteomics analysis for small cell populations. Here, the authors establish a robotically controlled chip-based nanodroplet processing platform and demonstrate its ability to profile the proteome from 10–100 mammalian cells...

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Bibliographic Details
Main Authors: Ying Zhu, Paul D. Piehowski, Rui Zhao, Jing Chen, Yufeng Shen, Ronald J. Moore, Anil K. Shukla, Vladislav A. Petyuk, Martha Campbell-Thompson, Clayton E. Mathews, Richard D. Smith, Wei-Jun Qian, Ryan T. Kelly
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03367-w

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https://doi.org/10.1038/s41467-018-03367-w

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