Fluorescence-Guided High-Grade Glioma Surgery More Than Four Hours After 5-Aminolevulinic Acid Administration

Fluorescence-Guided High-Grade Glioma Surgery More Than Four Hours After 5-Aminolevulinic Acid Administration

Background: Fluorescence-guided surgery (FGS) using 5-aminolevulic acid (5-ALA) is a widely used strategy for delineating tumor tissue from surrounding brain intraoperatively during high-grade glioma (HGG) resection. 5-ALA reaches peak plasma levels ~4 h after oral administration and is currently ap...

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Bibliographic Details
Main Authors: Georgios A. Maragkos, Alexander J. Schüpper, Nikita Lakomkin, Panagiotis Sideras, Gabrielle Price, Rebecca Baron, Travis Hamilton, Sameah Haider, Ian Y. Lee, Constantinos G. Hadjipanayis, Adam M. Robin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Neurology
Subjects:
fluorescence
5-ALA
glioma
glioblastomas
brain tumors
neuro-oncology
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.644804/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.644804/full

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