Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone

Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone

Resistance mechanisms of rho-associated kinase (ROCK) inhibitors are associated with the enhanced expression of cyclooxygenase-2 (COX-2). The therapeutic effects of ROCK on nervous system diseases might be enhanced by COX-2 inhibitors. This study investigated the synergistic effect of the combined u...

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Bibliographic Details
Main Authors: Xiao-lin Hou, Yan Chen, Hua Yin, Wei-gang Duan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; Rho kinase; fasudil; cyclooxygenase-2; celecoxib; spinal cord injury; NSFC grant; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=11;spage=1836;epage=1840;aulast=Hou

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=11;spage=1836;epage=1840;aulast=Hou

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