Methylene Blue Reduces Neuronal Apoptosis and Improves Blood-Brain Barrier Integrity After Traumatic Brain Injury

Methylene Blue Reduces Neuronal Apoptosis and Improves Blood-Brain Barrier Integrity After Traumatic Brain Injury

Objective: To investigate whether methylene blue (MB) treatment can reverse neuronal mitochondrial dysfunction caused by oxygen glucose deprivation/reoxygenation (OGD) injury and then investigate whether MB treatment can reduce neuronal apoptosis and improve blood-brain barrier (BBB) integrity in tr...

Full description

Bibliographic Details
Main Authors: Jun Shen, Wenqiang Xin, Qifeng Li, Yalong Gao, Lili Yuan, Jianning Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neurology
Subjects:
adenosine triphosphate
apoptosis
blood-brain barrier
methylene blue
reactive oxygen species
traumatic brain injury
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01133/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.01133/full

Similar Items