Heterogeneity of Human Mast Cells With Respect to MRGPRX2 Receptor Expression and Function

Heterogeneity of Human Mast Cells With Respect to MRGPRX2 Receptor Expression and Function

Mast cells and their mediators play a role in the control of homeostasis and in the pathogenesis of several disorders. The concept of rodent mast cell heterogeneity, initially established in the mid-1960s has been extended in humans. Human mast cells isolated and purified from different anatomic sit...

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Bibliographic Details
Main Authors: Gilda Varricchi, Antonio Pecoraro, Stefania Loffredo, Remo Poto, Felice Rivellese, Arturo Genovese, Gianni Marone, Giuseppe Spadaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
heart
histamine
leukotriene C4
mast cells
MRGPRX2
prostaglandin D2
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00299/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00299/full

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