Selection and characterization of a DNA aptamer that can discriminate between cJun/cJun and cJun/cFos.

The AP-1 family of transcriptional activators plays pivotal roles in regulating a wide range of biological processes from the immune response to tumorigenesis. Determining the roles of specific AP-1 dimers in cells, however, has remained challenging because common molecular biology techniques are un...

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Bibliographic Details
Main Authors: Ryan D Walters, David T McSwiggen, James A Goodrich, Jennifer F Kugel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4072727?pdf=render