Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy

Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy

Abstract Recent positron emission tomography (PET) studies have demonstrated the accumulation of tau PET tracer in the affected region of progressive supranuclear palsy (PSP) cases. To confirm the binding target of radiotracer in PSP, we performed an imaging-pathology correlation study in two autops...

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Bibliographic Details
Main Authors: Aiko Ishiki, Ryuichi Harada, Hideaki Kai, Naomi Sato, Tomoko Totsune, Naoki Tomita, Shoichi Watanuki, Kotaro Hiraoka, Yoichi Ishikawa, Yoshihito Funaki, Ren Iwata, Shozo Furumoto, Manabu Tashiro, Hironobu Sasano, Tetsuyuki Kitamoto, Yukitsuka Kudo, Kazuhiko Yanai, Katsutoshi Furukawa, Nobuyuki Okamura, Hiroyuki Arai
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Acta Neuropathologica Communications
Subjects:
PSP
Monoamine oxidase
Reactive astrocyte
Tau
PET
[18F]THK5351
Online Access:http://link.springer.com/article/10.1186/s40478-018-0556-7

Internet

http://link.springer.com/article/10.1186/s40478-018-0556-7

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