Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro

The sebaceous gland (SG) has been proposed to be replenished by pools of cells, including a population in the SG base, marked by Blimp1. Here, the authors show that Blimp1+ cells can establish an organoid model of the SG, which is regulated by c-Myc and can recapitulate the early stages of acne vulg...

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Bibliographic Details
Main Authors: Alona Feldman, Dzmitry Mukha, Itzhak I. Maor, Egor Sedov, Elle Koren, Yahav Yosefzon, Tomer Shlomi, Yaron Fuchs
Format: Article
Language:English
Published: Nature Publishing Group 2019-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10261-6