Club cell protein 16 in sera from trauma patients modulates neutrophil migration and functionality via CXCR1 and CXCR2

Club cell protein 16 in sera from trauma patients modulates neutrophil migration and functionality via CXCR1 and CXCR2

Abstract Background Club Cell protein (CC)16 correlates with lung injury and respiratory complications, which are in part triggered by polymorphonuclear leukocytes (PMNL) in severely traumatized patients (TP). CC16 exerts anti-inflammatory and immunosuppressive effects, however, its influence on PMN...

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Bibliographic Details
Main Authors: Baolin Xu, Andrea Janicova, Jan Tilmann Vollrath, Philipp Störmann, Lukas Martin, Ingo Marzi, Sebastian Wutzler, Frank Hildebrand, Sabrina Ehnert, Borna Relja
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Molecular Medicine
Subjects:
Trauma
Pneumonia
Neutrophils
Migration
ROS
Phagocytosis
Online Access:http://link.springer.com/article/10.1186/s10020-019-0115-0

Internet

http://link.springer.com/article/10.1186/s10020-019-0115-0

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