The HPA – immune axis and the immunomodulatory actions of glucocorticoids in the brain
In response to physiological and psychogenic stressors, the hypothalamic-pituitary adrenal (HPA) axis orchestrates the systemic release of glucocorticoids (GCs). By virtue of nearly ubiquitous expression of the GC receptor (GR) and the multifaceted metabolic, cardiovascular, cognitive and immunologi...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-03-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00136/full |