The HPA – immune axis and the immunomodulatory actions of glucocorticoids in the brain

In response to physiological and psychogenic stressors, the hypothalamic-pituitary adrenal (HPA) axis orchestrates the systemic release of glucocorticoids (GCs). By virtue of nearly ubiquitous expression of the GC receptor (GR) and the multifaceted metabolic, cardiovascular, cognitive and immunologi...

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Bibliographic Details
Main Authors: Marc-Andre eBellavance, Serge eRivest
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00136/full