Virus-encoded miRNAs in Ebola virus disease

Abstract Ebola virus (EBOV) is a negative-strand RNA virus that replicates in the cytoplasm and causes an often-fatal hemorrhagic fever. EBOV, like other viruses, can reportedly encode its own microRNAs (miRNAs) to subvert host immune defenses. miRNAs are short noncoding RNAs that can regulate gene...

Full description

Bibliographic Details
Main Authors: Janice Duy, Anna N. Honko, Louis A. Altamura, Sandra L. Bixler, Suzanne Wollen-Roberts, Nadia Wauquier, Aileen O’Hearn, Eric M. Mucker, Joshua C. Johnson, Joshua D. Shamblin, Justine Zelko, Miriam A. Botto, James Bangura, Moinya Coomber, M. Louise Pitt, Jean-Paul Gonzalez, Randal J. Schoepp, Arthur J. Goff, Timothy D. Minogue
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-23916-z