Baicalin Ameliorates Experimental Liver Cholestasis in Mice by Modulation of Oxidative Stress, Inflammation, and NRF2 Transcription Factor

Experimental cholestatic liver fibrosis was performed by bile duct ligation (BDL) in mice, and significant liver injury was observed in 15 days. Administration of baicalin in mice significantly ameliorates liver fibrosis. Experimental cholestatic liver fibrosis was associated with induced gene expre...

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Bibliographic Details
Main Authors: Kezhen Shen, Xiaowen Feng, Hao Pan, Feng Zhang, Haiyang Xie, Shusen Zheng
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2017/6169128