Treated dentin matrix induces odontogenic differentiation of dental pulp stem cells via regulation of Wnt/β-catenin signaling

Treated dentin matrix induces odontogenic differentiation of dental pulp stem cells via regulation of Wnt/β-catenin signaling

Treated dentin matrix (TDM) is an ideal scaffold material containing multiple extracellular matrix factors. The canonical Wnt signaling pathway is necessary for tooth regeneration. Thus, this study investigated whether the TDM can promote the odontogenic differentiation of human dental pulp stem cel...

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Bibliographic Details
Main Authors: Sirui Liu, Jingjing Sun, Shuai Yuan, Yanyu Yang, Yuping Gong, Ying Wang, Runying Guo, Xue Zhang, Yiming Liu, Hongyan Mi, Meiyue Wang, Mengzhe Liu, Rui Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-01-01
Series:Bioactive Materials
Subjects:
Dental pulp stem cells
Treated dentin matrix
GSK3β
Odontogenic differentiation
Wnt/β-catenin signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21002474

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http://www.sciencedirect.com/science/article/pii/S2452199X21002474

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