Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma

Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma

Background Anti-programmed death (PD)-1 therapy has recently been used in recurrent or metastatic (R/M) nasopharyngeal carcinoma (NPC). The long-term survival and its biomarkers responding to anti-PD-1 treatment in patients with R/M NPC remain unclear.Methods Patients with R/M NPC were enrolled betw...

Full description

Bibliographic Details
Main Authors: Yan Huang, Xi Chen, Hua Bao, Xue Wu, Hongyun Zhao, Shaodong Hong, Yunpeng Yang, Wenfeng Fang, Yuxiang Ma, Yang Shao, Ao Wang, Qingguang Lin, Wanxiangfu Tang
Format: Article
Language:English
Published: BMJ Publishing Group 2021-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/3/e002014.full

Internet

https://jitc.bmj.com/content/9/3/e002014.full

Similar Items