Retinal Functional and Structural Changes in the 5xFAD Mouse Model of Alzheimer’s Disease

Alzheimer’s disease is characterized by the aberrant deposition of protein in the brain and is the leading cause of dementia worldwide. Increasingly, there have been reports of the presence of these protein hallmarks in the retina. In this study, we assayed the retina of 5xFAD mice, a transgenic mod...

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Bibliographic Details
Main Authors: Jeremiah K. H. Lim, Qiao-Xin Li, Zheng He, Algis J. Vingrys, Holly R. Chinnery, Jamie Mullen, Bang V. Bui, Christine T. O. Nguyen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00862/full