NOX2β: A novel splice variant of NOX2 that regulates NADPH oxidase activity in macrophages.

Nox2 oxidase is one isoform in a family of seven NADPH oxidases that generate reactive oxygen species (ROS) and thereby contribute to physiological and pathological processes including host defense, redox signaling and oxidative tissue damage. While alternative mRNA splicing has been shown to influe...

Full description

Bibliographic Details
Main Authors: Craig B Harrison, Stavros Selemidis, Elizabeth Guida, Paul T King, Christopher G Sobey, Grant R Drummond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23118986/pdf/?tool=EBI