Identification of adenylyl cyclase isoforms mediating parathyroid hormone- and calcitonin-stimulated cyclic AMP accumulation in distal tubule cells

Identification of adenylyl cyclase isoforms mediating parathyroid hormone- and calcitonin-stimulated cyclic AMP accumulation in distal tubule cells

Abstract Background The distal convoluted tubule (DCT) is an important nephron site for parathyroid hormone (PTH) and calcitonin regulation of urinary divalent cation excretion. These hormones exert their effects on the DCT in substantial part through activation of adenylyl cyclase (AC); however, it...

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Bibliographic Details
Main Authors: Wararat Kittikulsuth, Peter A. Friedman, Alfred van Hoek, Yang Gao, Donald E. Kohan
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Nephrology
Subjects:
Distal convoluted tubule
Adenylyl cyclase
Calcitonin
Parathyroid hormone
Isoform
Online Access:http://link.springer.com/article/10.1186/s12882-017-0712-5

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http://link.springer.com/article/10.1186/s12882-017-0712-5

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