Chromosomal and plasmid-encoded factors of Shigella flexneri induce secretogenic activity ex vivo.

Shigella flexneri is a Gram-negative, facultative intracellular pathogen that causes millions of cases of watery or bloody diarrhea annually, resulting in significant global mortality. Watery diarrhea is thought to arise in the jejunum, and subsequent bloody diarrhea occurs as a result of invasion o...

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Bibliographic Details
Main Authors: Christina S Faherty, Jill M Harper, Terez Shea-Donohue, Eileen M Barry, James B Kaper, Alessio Fasano, James P Nataro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3500342?pdf=render