Case Report: Polyvinylpyrrolidone deposition disease from repeated injection of opioid substitution drugs: report of a case with a fatal outcome [version 2; peer review: 2 approved]

Background: Intravenous injection of oral opioid substitution drugs (OSD) is widespread among injecting drug users. Several OSDs contain the polymer polyvinylpyrrolidone (PVP) as an excipient. Parenterally administered PVP of high molecular weight may accumulate in tissues and organs. This phenomeno...

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Bibliographic Details
Main Authors: Ida Viken Stalund, Gro Nygard Riise, Friedemann Leh, Tormod Karlsen Bjånes, Lars Riise, Einar Svarstad, Sabine Leh
Format: Article
Language:English
Published: F1000 Research Ltd 2021-07-01
Series:F1000Research
Online Access:https://f1000research.com/articles/10-300/v2