Case Report: Polyvinylpyrrolidone deposition disease from repeated injection of opioid substitution drugs: report of a case with a fatal outcome [version 2; peer review: 2 approved]
Background: Intravenous injection of oral opioid substitution drugs (OSD) is widespread among injecting drug users. Several OSDs contain the polymer polyvinylpyrrolidone (PVP) as an excipient. Parenterally administered PVP of high molecular weight may accumulate in tissues and organs. This phenomeno...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2021-07-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/10-300/v2 |