A 30-Year Prospective Follow-Up Study Reveals Risk Factors for Early Death in Cartilage-Hair Hypoplasia

A 30-Year Prospective Follow-Up Study Reveals Risk Factors for Early Death in Cartilage-Hair Hypoplasia

Cartilage-hair hypoplasia (CHH) is a skeletal dysplasia with combined immunodeficiency, variable clinical course and increased risk of malignancy. Management of CHH is complicated by a paucity of long-term follow-up data, as well as knowledge on prognostic factors. We assessed clinical course and ri...

Full description

Bibliographic Details
Main Authors: Svetlana Vakkilainen, Mervi Taskinen, Paula Klemetti, Eero Pukkala, Outi Mäkitie
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
cancer
combined immunodeficiency
adult-onset immunodeficiency
lung disease
lymphoma
mortality
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01581/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01581/full

Similar Items