Catechol Groups Enable Reactive Oxygen Species Scavenging-Mediated Suppression of PKD-NFkappaB-IL-8 Signaling Pathway by Chlorogenic and Caffeic Acids in Human Intestinal Cells

Catechol Groups Enable Reactive Oxygen Species Scavenging-Mediated Suppression of PKD-NFkappaB-IL-8 Signaling Pathway by Chlorogenic and Caffeic Acids in Human Intestinal Cells

Chlorogenic acid (CHA) and caffeic acid (CA) are phenolic compounds found in coffee, which inhibit oxidative stress-induced interleukin (IL)-8 production in intestinal epithelial cells, thereby suppressing serious cellular injury and inflammatory intestinal diseases. Therefore, we investigated the a...

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Bibliographic Details
Main Authors: Hee Soon Shin, Hideo Satsu, Min-Jung Bae, Mamoru Totsuka, Makoto Shimizu
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Nutrients
Subjects:
chlorogenic acid
caffeic acid
interleukine-8
nuclear factor κB
protein kinase D
reactive oxygen species
catechol group
Online Access:http://www.mdpi.com/2072-6643/9/2/165

Internet

http://www.mdpi.com/2072-6643/9/2/165

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