Modular pathway engineering of key precursor supply pathways for lacto-N-neotetraose production in Bacillus subtilis

Modular pathway engineering of key precursor supply pathways for lacto-N-neotetraose production in Bacillus subtilis

Abstract Background Lacto-N-neotetraose (LNnT) is one of the important ingredients of human milk oligosaccharides, which can enhance immunity, regulate intestinal bacteria and promote cell maturation. Results In this study, the synthetic pathway of LNnT was constructed by co-expressing the lactose p...

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Bibliographic Details
Main Authors: Xiaomin Dong, Nan Li, Zhenmin Liu, Xueqin Lv, Jianghua Li, Guocheng Du, Miao Wang, Long Liu
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Biotechnology for Biofuels
Subjects:
Lacto-N-neotetraose
Bacillus subtilis
Modular pathway engineering
Human milk oligosaccharides
Online Access:http://link.springer.com/article/10.1186/s13068-019-1551-3

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http://link.springer.com/article/10.1186/s13068-019-1551-3

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