Production of Active Nonglycosylated Recombinant B-Chain of Type-2 Ribosome-Inactivating Protein from Viscum articulatum and Its Biological Effects on Peripheral Blood Mononuclear Cells

Type-2 ribosome-inactivating proteins, composed of a toxic A-chain and lectin-like B-chain, display various biological functions, including cytotoxicity and immunomodulation. We here cloned the lectin-like B-chain encoding fragment of a newly identified type-2 RIP gene, articulatin gene, from Viscum...

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Bibliographic Details
Main Authors: Tzu-Li Lu, Jing-Yuan Chuang, Jai-Sing Yang, Shau-Ting Chiu, Nai-Wan Hsiao, Mei-Chen Wu, Shih-Hsiung Wu, Ching-Hsiang Hsu
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2011/283747