Longitudinal serum biomarker screening identifies malate dehydrogenase 2 as candidate prognostic biomarker for Duchenne muscular dystrophy

Longitudinal serum biomarker screening identifies malate dehydrogenase 2 as candidate prognostic biomarker for Duchenne muscular dystrophy

Abstract Background Duchenne muscular dystrophy (DMD) is a fatal disease for which no cure is available. Clinical trials have shown to be largely underpowered due to inter‐individual variability and noisy outcome measures. The availability of biomarkers able to anticipate clinical benefit is highly...

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Bibliographic Details
Main Authors: Mirko Signorelli, Burcu Ayoglu, Camilla Johansson, Hanns Lochmüller, Volker Straub, Francesco Muntoni, Erik Niks, Roula Tsonaka, Anja Persson, Annemieke Aartsma‐Rus, Peter Nilsson, Cristina Al‐Khalili Szigyarto, Pietro Spitali
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Duchenne muscular dystrophy
Protein biomarkers
Prognostic biomarker
Rare diseases
Serum biomarkers
Online Access:https://doi.org/10.1002/jcsm.12517

Internet

https://doi.org/10.1002/jcsm.12517

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